Analysis of antimutagenic effect of a compositional preparation made from extracts of green tea leaves and Caucasian persimmon fruits

Abstract

Antimutagenic activity of a compositional preparation produced from extracts of green tea leaves and fruit of Caucasian persimmon was determined on the cell culture of human peripheral blood lymphocytes with modification of a mutation process induced by ionizing radiation and nitrosoguanidine. Antimutagenic efficiency of the preparation composites increases when the induced mutability is modified by factors of various physical and chemical nature. The comparative evaluation of their antimutagenic efficiency showed high antimutagenic activity of the composites of the preparation produced from extracts of green tea leaves and Caucasian persimmon fruit. Therewith the strength of this effect is dependent on dose intensity.